Home > Campaigns > Animal experiments > Mad Science Awards > August 2000

ANIMAL AID AWARDS
FOR MAD SCIENCE 2000

Some 900 million animals are killed each year in the UK to satisfy the human palate. The majority are subjected to intensive rearing regimes - whether it be chickens in rank, over-crowded sheds; or dairy cows selectively bred to carry freakishly large quantities of milk and whose calves are stolen from them within a day or two. Even sheep on hills are victims of intensification. Thanks to over-breeding, neglect and low shepherd numbers, some 15 to 20 per cent of all new-born lambs are dead within days.

But the suffering for sheep, pigs, cattle, turkeys and chickens doesn't end there. As Animal Aid's Mad Science Awards for 2000 reveal, thousands of these animals are made to endure a range of perverse torments in vivisection laboratories throughout the country in an attempt to 'improve' factory farming.

Squeezing profit

Sometimes the purpose is to learn how to squeeze more profit from animals who are already at their physiological limits. Other times the experiments are an attempt to remedy welfare problems that are a direct consequence of the punishing way in which the animals are impregnated, fattened, transported and slaughtered.

The size of the national sheep flock has increased dramatically over the past 20 years, leading to serious welfare problems as well as financial pressures upon farmers. And yet invasive experiments designed to improve sheep fertility continue. An example we highlight is the 14 pregnant ewes at London University who were part-starved for 70 days, subjected to surgery, had tubes inserted into veins and arteries for several more weeks, and were even restricted in their oxygen supply by having bags put over their heads... all this prior to them and their foetuses being killed.

Starving experiments

Another starving experiment involving the insertion of tubes was conducted at the Rowett Institute, Aberdeen. This time the victims were one year old male cattle. The idea was to compare the way cattle and sheep use certain food sources.

Disease amongst shed-reared animals is the norm, not least amongst pigs, the majority of whom eke out their existence in crowded units made of concrete and metal. Despite there being an endless supply of disease victims languishing in these commercial units, Belfast researchers removed 16 newborn piglets from their mothers - even before they could receive their first antibody-rich colostrum - and injected them with two types of virus. Two animals died and others became thin, immobilised and weak. All were then killed and examined.

One million broiler chickens (these are the ones reared for meat rather than to produce eggs) die each year while transported to killing plants. They succumb to heat or cold, or to the sheer stress of being thrust into plastic crates and driven for several hours.

Researchers at the Roslin Institute Edinburgh, where abusive animal cloning experiments take place, put 90 caged chickens in a wind tunnel for three hours. Some had temperature-measuring devices implanted in their bodies. Temperatures were raised and lowered and the birds sprayed with water.

Chicken pain tests

Another Roslin experiment on chickens involved injecting into the ankle of more than 200, a substance known to cause acute pain. The idea was to mimic the joint pain that is endemic in commercial chickens as a result of the way these over-large birds are rapidly fattened. Some of the chickens also received an injected pain killer. One of the three drugs tried out actually made their suffering worse.

It is plainly evident why chickens suffer chronic leg pain - a condition that is often lethal because it renders the birds unable to walk to the feed and water units within the factory sheds. The answer is not an increased diet of toxic pharmaceuticals but to desist from abusing them.

Meanwhile, from Addlestone, Surrey comes a reminder of the heavy price a range of species continues to pay for the BSE crisis, an epidemic that is the product of industry greed and stupidity. Ten pigs were injected with brain material obtained from cows suffering BSE. Injection sites were the pigs' brains, abdomens and veins. Some suffered BSE-like symptoms, demonstrating to the researchers that when you inject diseased brain material into the bodies of another species they get sick. What an amazing discovery!

The big lie

This year's Mad Science Awards are well deserved. They highlight a phenomenon that has long been virtually ignored: the conduct of one form of animal abuse in order to perpetuate another... vivisection in the service of factory farming. They also illuminate the Big Lie that is propounded by advocates of animal experiments - the lie that, when not done to save human lives, vivisection is carried out for the benefit of other animals.

Summaries of the Award Winners

Paper 1: Bristol University: lamb castration experiments

At Bristol University, 216 lambs aged 4 to 6 days were used for research (funded by the Ministry of Agriculture, Fisheries and Food) into ways to measure the amount of pain felt during castration. Lambs are routinely castrated to control breeding and in the belief that it may improve the value of their meat.. 162 of the lambs were castrated with or without anaesthetic by one of three methods: a tight rubber ring squeezed onto their scrotum; a rubber ring combined with using a clamp on their scrotum to crush the blood vessels supplying their testicles; or surgery to cut open their scrotum and tear out their testicles. The amount of pain they were suffering was then compared by studying their behaviour - including their reaction when their scrotum was pressed; measuring how hard a blunt pin had to be pressed against their foot before they lifted it; and taking blood samples to measure the level of a stress-hormone. Although it is plainly obvious that lambs suffer pain and distress during this type of research and when they are castrated on farms, preventing or discouraging this mutilation was not discussed.

Thornton PD & Waterman-Pearson AE (1999) 'Quantification of the pain and distress responses to castration in young lambs', Research in Veterinary Science 66(2): 107-118

Paper 2: London University: pregnant ewes starved and surgically invaded

At London University, 14 pregnant ewes were experimented on to see how depriving them of food affected the development of some hormone-producing parts of their unborn foetuses - with possible long-term health consequences. Half of the ewes were allowed only 85% of their recommended nutritional requirements for the first 70 days of their pregnancy. A little more than a month later, all 14 ewes were operated on to expose their uterus and partly remove their foetus. Tubes were inserted into an artery and a vein in the foetus, into the mother's uterus, and into one of the mother's veins. The foetus was then replaced in the mother's womb, the cuts made to the ewe were closed, and the tubes were used to take samples over a period of 2 weeks. On 3 occasions during this period, a bag was put over each ewe's head and for a period of one hour the amount of oxygen was restricted and the effect on substances in the blood of their foetuses was measured. Once these tests were complete, the ewes and foetuses were killed and some of their organs measured and weighed to see whether the under feeding had affected their growth. The obvious conclusion that if sheep are to be farmed they should be fed adequately is not discussed.

Hawkins P; Steyn C; McGarrigle HHG; Saito T; Ozaki T; Stratford LL; Noakes DE & Hanson MA (1999) 'Effect of maternal nutrient restriction in early gestation on responses of the hypothalamic-pituitary-adrenal axis to acute isocapnic hypoxaemia in late gestation fetal sheep'. Experimental Physiology; 85(1): 85-96

Paper 3: MAFF: brain experiments on pigs

As part of research funded by MAFF in Addlestone, Surrey, 21 young pigs were used in tests to see whether BSE would transfer to pigs. The pigs were injected with a solution of salt, in 10 cases containing homogenised brains from cows with BSE. The injections were made at three sites - into their brain, into a vein, and into their abdomen Five of the pigs injected with BSE tissues were allowed to suffer BSE-like symptoms (behavioural changes and difficulty walking) for some time before being killed once they were terminally ill. The remaining pigs were killed after periods of up to five years, to allow their brain tissues to be examined. The research seems to show that BSE can be transmitted to pigs if they are injected with the brain tissue of infected cows.

Ryder SJ; Hawkins SAC; Dawson M & Wells GAH (2000) 'The neuropathology of experimental bovine spongiform encephalopathy in the pig'. Journal of Comparative Pathology; 122(2/3): 131-143

Paper 4: Turkey slaughter tests at Bristol

Research at Bristol University funded by MAFF used 1115 turkeys with different stunning currents to compare how effective the stunning was and how much damage was caused to their bodies. The turkeys were hung by their legs from a shackle and the electric current was passed through their bodies by immersing their heads in a waterbath. If the charge stopped the turkey's heart, the bird was transferred to a processing line and killed by cutting both carotid arteries in his/her neck. Otherwise they were left suspended on the shackle until they started breathing, then laid on their sides until they could lift their heads. They were then stunned again and their throats cut to allow them to bleed to death. The time before the turkeys started to recover was found to be less than the time found previously between neck cutting and brain death. This suggests that even if there is no delay between stunning and neck cutting, turkeys will regain consciousness while they are bleeding to death. Greater delays are more likely in the far from ideal conditions of a commercial slaughter line. The lower electrical current frequencies were more likely to cause the turkeys' hearts to stop, and so reduce their suffering - but were also more likely to damage their bodies, mainly through haemorrhages and broken bones. Substantial concern is expressed over the loss of value of their bodies - but less concern for the additional suffering that must be caused by these major injuries.

Wilkins LJ; Gregory NG & Wotton SB (1999) 'Effectiveness of different stunning regimes for turkeys and consequences for carcase quality'. British Poultry Science; 40: 478-484

Paper 5: Edinburgh: pain tests on chickens' legs

At the Roslin Institute in Edinburgh, 216 young chickens (12 weeks old) were used to assess whether certain pain-killers would be useful in further research into how much pain chickens suffer from joint diseases. These joint diseases are commonly suffered by commercial breeds, and make them unable to walk. Pain was deliberately produced by injecting into the left ankle joint of each chicken a substance known to produce an acute arthritic condition similar to gout. For some chickens the injection also included one of the three pain-killers being tested. After one hour, the chickens were watched for a further hour to assess from their activities how much pain they were suffering. No information is given about what happened to them after this period, or for how much longer they were left in pain. The conclusion was that none of the pain-killers reduced the pain, and that one made the pain even worse. No comment is made about the plight of huge numbers of chickens suffering continual joint pain in intensive farms.

Gentle MJ; Hocking PM; Bernard R & Dunn LN (1999) 'Evaluation of intraarticular opioid analgesia for the relief of articular pain in the domestic fowl'. Pharmacology Biochemistry and Behavior; 63(2): 339-343

Paper 6: Cattle starved in Aberdeen

At the Rowett Research Institute in Aberdeen, five steers (one year old) were used in research on starved cattle. They had two tubes inserted into their stomachs. They were then deprived of all normal food while nutrients were supplied through one tube to their stomachs and samples taken through the other. Two of the steers were starved completely (given essential trace minerals and vitamins only) for two days; then they were allowed increasing amounts of glucose. The fate of the steers at the end of the experiment is not described. The results indicated that there is a species difference between cattle and sheep in the way they use some nutrients.

Orskov ER; Meehan DE; MacLeod NA & Kyle DJ (1999) 'Effect of glucose supply on fasting nitrogen excretion and effect of level and type of volatile fatty acid infusion on response to protein infusion in cattle'. British Journal of Nutrition; 81(5): 389-393

Paper 7: Piglets given lethal virus in Belfast

In Belfast, 16 piglets were deprived of their mothers' colostrum and at one or two days old were infected with two types of virus (porcine circovirus type 2 and porcine parvovirus). The aim was to produce the symptoms of a severe illness, known as post-weaning multi-systemic wasting syndrome (PMWS), that over the past decade has been affecting farmed pigs in various parts of the world. The piglets were infected with one or both viruses. Two piglets died during the experiment, and others became ill (they were lethargic, stopped eating, were reluctant to move, stood with their heads lowered, and became thin). The surviving piglets were killed three to four weeks after being infected, and samples of their organs were taken for examination. Some were found to have damage to their liver, kidneys, lungs, brain, lymph nodes, and other parts of their bodies. The research was conducted at the Veterinary Sciences Division, Department of Agriculture for Northern Ireland and Queen's University of Belfast.

Kennedy S; Moffett D; McNeilly F; Meehan B; Ellis J; Krakowka S & Allan GM (2000) 'Reproduction of lesions of postweaning multisystemic wasting syndrome by infection of conventional pigs with porcine circovirus type 2 alone or in combination with porcine parvovirus'. Journal of Comparative Pathology 122(1): 9-24

Allan GM; Kennedy S; McNeilly F; Foster JC; Ellis JA; Krakowka SJ; Meehan B & Adair BM (1999) 'Experimental reproduction of severe wasting disease by co-infection of pigs with porcine circovirus and porcine parvovirus'. Journal of Comparative Pathology; 121(1):1-1

Paper 8: Liverpool University: stress and reproduction tests

At Liverpool University, 20 ewes were used to research how stress during transport affected production of a reproductive hormone. Ten of the ewes were anaesthetised while their ovaries were removed and an implant to supply a hormone was inserted under their skin. Four larger implants were later inserted under their skin and left for between one and two days. The timing of ovulation in all the ewes was controlled by hormones, delivered by devices inserted into their vagina for periods of 10 days. A tube was inserted into their jugular vein and used to take blood samples. As part of one experiment, the ewes were driven in a truck for four hours and the effect on hormones in their blood was measured. Researchers concluded that the stress of transporting ewes inhibits their production of a hormone and so reduces their fertility. The research was conducted at Liverpool University Department of Veterinary Clinical Science and Animal Husbandry, Neston, South Wirral.

Dobson H; Tebble JE; Phogat JB & Smith RF (1999) 'Effect of transport on pulsatile and surge secretion of LH in ewes in the breeding season'. Journal of Reproduction and Fertility; 116(1): 1-8

Paper 9: Invasive pregnancy tests in Glasgow

In Glasgow, 40 ewes were subjected to research into how ultrasound can be used to check the number of ovulations in sheep. The aim was to test this method on sheep who have a gene which produces higher ovulation rates than normal. Eighteen of the ewes were made to stand in a crate while an ultrasound probe wrapped in a condom was pushed into their rectums and used to examine their ovaries. The other 22 were held on their backs in a crate, with their back legs pulled towards their head and tied to the bars to prevent them kicking the researcher or the equipment. Again an ultrasound probe was pushed into their rectums and used to examine their ovaries. All the ewes were conscious during the examination - which in a few cases caused a small amount of bleeding from their rectum. Following the examinations, the ewes were killed and their ovaries removed for investigation. The research was conducted at Glasgow University Veterinary School, Glasgow and the Scottish Agricultural College, Auchincruive.

Dickie AM; Paterson C; Anderson JLM & Boyd JS (1999) 'Determination of corpora lutea numbers Booroola-Texel ewes using transrectal ultrasound'. Theriogenology 51(7): 1209-1224

Paper 10: Edinburgh: wind tunnel tests on chickens

At the Roslin Institute in Edinburgh, 80 broiler chickens at slaughter weight (six weeks old) were used to establish whether they were more likely to die during transport if they were wet. Each year more than one million broiler chickens die while being transported to slaughterhouses - many as a result of over-heating or from cold. The chickens were put in transport cages in a wind tunnel at different temperatures for three hours (representing the average transport time of 2.7 hours). Temperatures taken from their rectums or from a device implanted in their bodies showed that when they were sprayed with water they became colder, in some cases cold enough to have died from hypothermia. These problems are exacerbated by the industry practice of starving birds for up to six hours before transportating them. A reappraisal of vehicle ventilation design to limit wetting of broilers by road-spray is recommended.

Hunter RR; Mitchell MA & Carlisle AJ (1999) 'Wetting of broilers during cold weather transport: a major source of physiological stress?' British Poultry Science; 40(Suppl): S48-S49

Paper 11: Aberystwyth: weighted balloons and glass spheres inserted into sheep

At the Institute of Biological Sciences, University of Wales, Aberystwyth, 21 adult sheep were used to research the control of contractions in the first part of their stomachs. While anaesthetised, 14 of the sheep had a hole 12cm across (nearly five inches) cut into this part of their stomach and were then fitted with a plastic plug. After two months or more, the sheep were trained to "stand quietly" while changes in pressure in four parts of their stomachs were measured using weighted balloons put into their stomachs. The remaining seven sheep were anaesthetised while probes were placed around arteries supplying their stomachs, to allow blood-flow to be measured. These sheep also had a water-filled balloon weighted with glass spheres pushed through a hole into their stomachs. The sheep then had various substances injected, and their stomach contractions were monitored and blood samples were taken for analysis.

Care AD; Abbas SK; Harmeyer J & Boivin R (1999) 'The relaxant effects of parathyroid hormone(1-34) and parathyroid hormone-related protein(1-34) on ovine reticulo-ruminal smooth muscle in vivo'. Experimental Physiology; 84(4): 665-675

Paper 12: Edinburgh: fourteen month brain tests on rams

At a Medical Research Council unit in Edinburgh, 12 adult rams were used in experiments to discover which part of their brain controls hormone changes in response to changing day-length. A part of each ramıs brain was cut out, and an aluminium foil barrier was put into his brain to separate two of its parts. As expected, this caused the rams to urinate more than usual, their testicles to malfunction, and they became fat. Even so, they were said to be in Œgood healthı. The rams were kept permanently in rooms with artificial lighting. For the nearly 14 months of this experiment the lights were kept on for either eight or 16 hours each day. Twice each week a blood sample was taken from the jugular vein of each ram, and on three occasions a tube was inserted into their jugular vein and used to take 24 blood samples (at hourly intervals). The experiment was conducted at the MRC Reproductive Biology Unit, Centre for Reproductive Biology, Edinburgh.

Lincoln GA & Clarke IJ (2000) 'Role of the pituitary gland in the development of photorefractoriness and generation of long-term changes in prolactin secretion in rams'. Biology of Reproduction; 62(2): 432-438

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